国際バイオ特論ⅠDr. Hiroshi Maeda 【230009】 第3回

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Lecture 3: Specialized metabolism and plant synthetic biology

内容

Plants usually have to live where they initially germinated. To circumvent this physical constrain, complex metabolic machineries have evolved during the plant evolution, which allow plants to synthesize a tremendous array of chemical compounds, known as plant natural products or specialized metabolites. This lecture will first provide overview of different classes of plant specialized metabolites and their functions in both plant and human physiology. Then, we will focus on one particular plant natural product, morphine alkaloid, to discuss how this complex chemical is synthesized from an aromatic amino acid tyrosine. We will also study how the knowledge obtained in plant systems was utilized to synthesize this complex chemical in heterologous hosts (e.g. yeast) through synthetic biology.  The seminar will end with class discussion to identify current limitations and potential future targets of plant synthetic biology, by utilizing metabolic maps each student drew from CO2 to morphine during the three lectures.

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回数 日付 限目 時間割内容 担当
1回目 11月28日 2限目 国際バイオ特論ⅠDr. Hiroshi Maeda 【230009】 Dr. Hiroshi Maeda

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